Cestmir Altaner Selected Research

Cytosine Deaminase

1/2022	Gene-Directed Enzyme/Prodrug Therapy of Rat Brain Tumor Mediated by Human Mesenchymal Stem Cell Suicide Gene Extracellular Vesicles In Vitro and In Vivo.
1/2019	Prodrug suicide gene therapy for cancer targeted intracellular by mesenchymal stem cell exosomes.
1/2019	Mesenchymal Stem Cell Exosome-Mediated Prodrug Gene Therapy for Cancer.
9/2014	Mesenchymal stem cells expressing therapeutic genes induce autochthonous prostate tumour regression.
3/2014	Complete regression of glioblastoma by mesenchymal stem cells mediated prodrug gene therapy simulating clinical therapeutic scenario.
5/2012	Human adipose tissue-derived mesenchymal stem cells expressing yeast cytosinedeaminase::uracil phosphoribosyltransferase inhibit intracerebral rat glioblastoma.
1/2010	Adipose tissue-derived mesenchymal stem cells expressing prodrug-converting enzyme inhibit human prostate tumor growth.
10/2008	Cytosine deaminase expressing human mesenchymal stem cells mediated tumour regression in melanoma bearing mice.

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Cestmir Altaner Research Topics

Disease

15	Neoplasms (Cancer) 01/2022 - 07/2007
4	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 05/2010
3	Chronic Limb-Threatening Ischemia 04/2013 - 01/2012
2	Neoplasm Metastasis (Metastasis) 01/2021 - 10/2011
2	Prostatic Neoplasms (Prostate Cancer) 09/2014 - 01/2010
2	Colonic Neoplasms (Colon Cancer) 10/2008 - 07/2007
1	Brain Neoplasms (Brain Tumor) 01/2022
1	Retroviridae Infections (Infection, Retrovirus) 04/2020
1	Adenocarcinoma 09/2014
1	Gangrene 04/2013
1	Ischemia 04/2013
1	Pain (Aches) 01/2012
1	Neoplasm Micrometastasis 01/2010
1	Melanoma (Melanoma, Malignant) 10/2008

Drug/Important Bio-Agent (IBA)

11	ProdrugsIBA 01/2022 - 07/2007
9	Flucytosine (Ancobon)FDA Link 01/2022 - 07/2007
8	Cytosine DeaminaseIBA 01/2022 - 10/2008
5	uracil phosphoribosyltransferaseIBA 09/2014 - 10/2008
4	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 01/2010
3	TransferasesIBA 01/2022 - 01/2019
3	EnzymesIBA 01/2022 - 11/2008
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2019
2	Ganciclovir (Cytovene)FDA LinkGeneric 04/2020 - 04/2010
2	Thymidine KinaseIBA 04/2020 - 04/2010
2	UracilIBA 01/2019 - 01/2019
2	CytokinesIBA 10/2011 - 05/2010
1	Conditioned Culture MediaIBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2021
1	Indicators and Reagents (Reagents)IBA 01/2018
1	Antineoplastic Agents (Antineoplastics)IBA 09/2014
1	Oxygen (Dioxygen)IBA 01/2012
1	Proteins (Proteins, Gene)FDA Link 10/2011
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 05/2010
1	Chemokine CXCL12IBA 05/2010
1	Cytotoxins (Cytolysins)IBA 10/2008

Therapy/Procedure

11	Therapeutics 01/2022 - 11/2008
2	Drug Therapy (Chemotherapy) 09/2019 - 07/2007
1	Investigational Therapies (Experimental Therapy) 01/2019
1	Intravenous Injections 09/2014
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 04/2013
1	Cell Transplantation 04/2013
1	Surgical Amputation (Amputations) 01/2013
1	Injections 05/2012
1	Intravenous Administration 01/2010